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Hello!
My name is Marina Kalmykova, I live in Tyumen region. I am a mother of five sons. Tragically, my oldest son Dima died in 2003. Then we had to face another problem. In June 2007 my youngest son Serezha had vaccinations, and two weeks later he developed health problems. From active and happy child he turned into a tired sad boy who had no appetite. Our visits to doctors were fruitless. We were simply told that he had "some kind of infection", and the doctors refused to test Serezha. This lasted several months. And on November 2 I called ambulance that took us to Zavodoukovsky hospital, and based on puncture results, Serezha was diagnosed with acute leukemia.
For almost eight months we stayed at Hematology Unit of Regional Clinical Hospital in Tyumen. Serezha was discharged on June 24, 2008, but in April 2009 he had a relapse. Once again we were admitted to the hospital for chemotherapy. Now my Serezha needs bone marrow transplantation to recover fully. The donor search produced no results. All three Serezha's brothers do not match as donors. We are now at R. Gorbacheva Pediatric Hematology and Transplantology Institute. Since Serezha's father died in 2004, only I can be my son's bone marrow donor.
I am asking for your help, because we need to raise a lot of money for the special equipment for haploidentical transplantation. Of all my older sons, only second one has a full-time job. The third is a student at a trade school. In our town, the wages can only cover bare necessities. Please help me save my son!

Respectfully,
Marina Kalmykova
Contact phone:
+7 (981) 892-78-38

Medical conclusion

Update as of January 24, 2010. Sergei goes for weekly tests and feels relatively well. At the end of January he is planned to be hospitalized for examination and a puncture at Tyumen Regional Clinical hospital. For now he has not been able to receive Gleevec for free, and the supply of the drug that he received at BMT clinic will run out in a week.
In addition, he needs to continue taking anti-nausea drugs because he does not tolerate Gleevec well.

Update as of May 30, 2010. According to information from Serezha's web site, on April 27th he and his mom arrived at Wurzburg University clinic for haploidentical bone marrow transplantation. Unfortunately, on April 19th during the tests at the clinic, it was discovered that Serezha had a relapse.
After undergoing anti-relapse chemotherapy, Serezha is recovering while the doctors are waiting for the puncture results

Update as of June 24, 2010. Haploidentical bone marrow transplantation was scheduled for June 26th.

Update as of August 25, 2010. Serezha recovered after transplantation and was discharged for outpatient monitoring. He feels well.

Update as of September 7, 2010. Based on information from Serezha's site, donor’s cell percentage fell to 20-30%. He is planned to undergo donor's lymphocyte infusion and a puncture.

Update as of November 23, 2010. Sergei was able to overcome a relapse and viral complication, now he is transferred to a day hospital.

Update as of January 15, 2011. The treatment in Germany is continuing. Serezha underwent donor's lymphocyte infusion, and three more are planned. He feels well.

Update as of February 28, 2011. Due to another drop in donor's bone marrow percentage, new donor's lymphocyte infusion was scheduled. Serezha will stay at the clinic for now.

Update as of March 17, 2011. According to Serezha's volunteers, he will be discharged from the clinic and return home. Serezha will be monitored in Yekaterinburg and will regularly forward blood samples to Wurzburg for tests. In addition, he will need to come to Wurzburg every 8 weeks for cell infusions.

Update as of June 2, 2011. In Tyumen, Serezha was operated and the tumor was removed. He then traveled with his mom to R. Gorbacheva Pediatric Hematology & Transplantation Institute for examination and further treatment. The specialist from the Institute will review histology and the treatment will depend on its results. Serezha feels relatively well.

Update as of June 13, 2011. Serezha started undergoing tests at R. Gorbacheva Pediatric Hematology & Transplantation Institute. Histology of removed neoplasm was reviewed and extramedullary leukemia relapse was confirmed. He then had tests for chimerism (percentage of donor's bone marrow) and a puncture is planned. Based on puncture results, further treatment will be determined. Serezha feels well.

Update as of October 31, 2011. Serezha underwent radiation therapy locally and came in for planned treatment at R. Gorbacheva Pediatric Hematology & Transplantation Institute. Based on test results, he is in complete remission. Serezha has no GVHD and feels well. He is taking Dasatinib. Serezha already returned home where he is monitored locally.

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